EU CHMP

EMA's Final Call On Alzheimer's Drug Leqembi Imminent

EMA's Final Call On Alzheimer's Drug Leqembi Imminent

 

Patient representatives are due to have their say today at a high-stakes meeting at the European Medicines Agency, which, after re-examining its previous rejection of Leqembi, is expected to deliver its final decision on whether the drug should be approved for marketing in the EU.

EMA Seeks Feedback On COI Policy Changes Following Legal Rulings

EMA Seeks Feedback On COI Policy Changes Following Legal Rulings

 

The European Medicines Agency is conducting a public consultation on proposed revisions to its policy on how it handles any conflicts of interest of its scientific committee members and experts.

Astellas Withdraws Izervay’s European Approval Filing

Astellas Withdraws Izervay’s European Approval Filing

 
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Decision contrasts with successful journey in the US, where it was approved with Fast Track designation in 2023. Astellas says its considering “every potential action” to bring GA drug to patients in Europe.

EU CHMP Opinions And MAA Updates

EU CHMP Opinions And MAA Updates

 

This is an update of recommendations from the European Medicines Agency's Committee for Medicinal Products for Human Use on the authorization of new medicines in the EU, and updates on EU marketing authorization changes recommended by the CHMP.


Hemophilia Drug Alhemo Among 10 New Drugs Set For EU Approval

Hemophilia Drug Alhemo Among 10 New Drugs Set For EU Approval

 

Novo Nordisk’s Alhemo and Ionis/AstraZeneca’s orphan drug Wainzua are among 10 new medicines that the European Medicines Agency has recommended for pan-EU approval this month.

EMA Schedules High-Stakes Meetings With Drug Makers

EMA Schedules High-Stakes Meetings With Drug Makers

 

The sponsors of medicines that are nearing the end of the regulatory review cycle in the EU could this week be asked to explain why the European Medicines Agency should recommend approving their products.

EU Decision Time For Hemophilia Drug Concizumab & 10 Other Products

EU Decision Time For Hemophilia Drug Concizumab & 10 Other Products

 

Concizumab sponsor Novo Nordisk and a number of other companies could soon learn whether or not the European Medicines Agency will give their respective drugs the marketing thumbs up.

EU HTA Regulation: Views Wanted On Draft Rules On Joint Scientific Consultations

EU HTA Regulation: Views Wanted On Draft Rules On Joint Scientific Consultations

 

A newly published draft implementing act sets out the procedural rules for the joint scientific consultations that are foreseen by the EU’s Health Technology Assessment Regulation.


New EU Approvals

New EU Approvals

 

The Pink Sheet's list of EU centralized approvals of new active substances has been updated to add four new products, including Anzupgo, LEO Pharma's treatment for moderate to severe chronic hand eczema in adults for whom topical corticosteroids are inadequate or inappropriate.

EMA Discusses Fatal Events That Prompted Pfizer To Pull Oxbryta From Global Markets

EMA Discusses Fatal Events That Prompted Pfizer To Pull Oxbryta From Global Markets

 

The company’s decision to withdraw the drug was based on “the totality of clinical data that now indicates the overall benefit of Oxbryta no longer outweighs the risk in the approved sickle cell patient population.”

UK MHRA First-Half New Drug Approvals Show Overwhelming Use Of EU Reliance Procedures

UK MHRA First-Half New Drug Approvals Show Overwhelming Use Of EU Reliance Procedures

 
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The UK regulator approved 16 medicines containing a new active substance in the first half of this year, while the European Commission issued marketing authorizations for 20 NAS-containing drugs.

EU CHMP Opinions And MAA Updates

EU CHMP Opinions And MAA Updates

 

This is an update of recommendations from the European Medicines Agency's Committee for Medicinal Products for Human Use on the authorization of new medicines in the EU, and updates on EU marketing authorization changes recommended by the CHMP.


Orphans Elahere, Hetronifly & Hympavzi Among Eight New Products Set For EU Approval

Orphans Elahere, Hetronifly & Hympavzi Among Eight New Products Set For EU Approval

 

The European Medicines Agency has recommended the pan-EU approval of three rare disease drugs: Pfizer’s Hympavzi, Henlius Biotech’s Hetronify and ImmunoGen’s Elahere in addition to five other new medicines.

UK MHRA To Retain Multiple Approval Pathways From 2025

UK MHRA To Retain Multiple Approval Pathways From 2025

 
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Reliance procedures have been used for most recent new drug approvals, and will continue to be employed in future, although the national approval route will play a key role in promoting innovation and protecting public health, says the UK regulator.

EU Decision Time For Orphan Drugs Marstacimab, Serplulimab And Mirvetuximab Soravtansine

EU Decision Time For Orphan Drugs Marstacimab, Serplulimab And Mirvetuximab Soravtansine

 

The European Medicines Agency is this week expected to decide whether to recommend for pan-EU marketing approval for Pfizer’s marstacimab, Henlius Biotech’s serplulimab and ImmunoGen’s mirvetuximab soravtansine.

New EU Filings

New EU Filings

 

Sugemalimab, from CStone Pharmaceuticals/EQRx, for use in combination with chemotherapy as first-line treatment for metastatic non-small cell lung cancer, is among the latest drugs that have been filed for review by the European Medicines Agency for potential EU marketing approval.